DOXORUBICIN-INDUCED PLATELET ACTIVATION AND CLEARANCE RELIEVED BY SALVIANOLIC ACID COMPOUND: NOVEL MECHANISM AND POTENTIAL THERAPY FOR CHEMOTHERAPY-ASSOCIATED THROMBOSIS AND THROMBOCYTOPENIA

Doxorubicin (Dox) is a widely utilized chemotherapeutic; however, it carries side effects, including drug-induced immune thrombocytopenia (DITP) and increased risk of venous thromboembolism (VTE).Currently, the mechanisms for Dox-associated DITP and VTE are poorly understood, and Collections an effective inhibitor to relieve these complications rem

Five species of anuran amphibians, all belonging to the family Hylidae, were collected at Praia das Neves, municipality of Presidente Kennedy, southeastern Brazil,.The species were represented by four genera: Scinax, Hyla, Aparasphenodon, and Trachycephalus.Four species (A.brunoi, Hyla albomarginata, Scinax altera, and Lip Pencil S.cuspidatus) were

IntroductionWe report a very unique clinical presentation of a patient who complained, after a left parietal brain damage, about feeling tactile stimulations on his right upper limb without being able to localize them.MethodsUsing a single case study approach, we report three experiments relying on several custom-made tasks to explore the different